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Claus Cursiefen Selected Research

Neoplasms (Cancer)

12/2023Combined Osteopontin Blockade and Type 2 Classical Dendritic Cell Vaccination as Effective Synergetic Therapy for Conjunctival Melanoma.
1/2022New Therapeutic Approaches for Conjunctival Melanoma-What We Know So Far and Where Therapy Is Potentially Heading: Focus on Lymphatic Vessels and Dendritic Cells.
9/2015A Novel Model of Metastatic Conjunctival Melanoma in Immune-Competent Mice.
2/2015Antilymphangiogenic therapy to promote transplant survival and to reduce cancer metastasis: what can we learn from the eye?
4/2014Autocrine impact of VEGF-A on uveal melanoma cells.
5/2013Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases.
2/2013Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1.
1/2011Intravital two-photon microscopy of immune cell dynamics in corneal lymphatic vessels.
8/2010Intraocular lymphatics in ciliary body melanomas with extraocular extension: functional for lymphatic spread?
7/2010Genetic heterogeneity of lymphangiogenesis in different mouse strains.
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Claus Cursiefen Research Topics

Disease

41Corneal Neovascularization
12/2022 - 10/2002
18Cataract (Cataracts)
04/2024 - 07/2012
17Glaucoma
04/2024 - 08/2013
17Inflammation (Inflammations)
05/2023 - 04/2004
17Fuchs' Endothelial Dystrophy
03/2023 - 12/2007
15Neoplasms (Cancer)
12/2023 - 04/2004
11Keratoconus
01/2023 - 02/2006
11Neoplasm Metastasis (Metastasis)
09/2015 - 04/2004
8Wounds and Injuries (Trauma)
04/2024 - 07/2002
7Edema (Dropsy)
03/2024 - 08/2019
7Melanoma (Melanoma, Malignant)
12/2023 - 05/2009
7Corneal Diseases (Corneal Disease)
02/2023 - 10/2009
7Macular Degeneration (Age-Related Maculopathy)
01/2022 - 12/2007
7Dry Eye Syndromes (Dry Eye Syndrome)
05/2021 - 12/2012
7Macular Edema
07/2020 - 03/2016
6Corneal Injuries
01/2024 - 03/2013
6Keratitis
11/2017 - 07/2002
5Retinal Detachment (Retinal Detachments)
04/2024 - 09/2017
5Uveitis
05/2023 - 04/2014
5Corneal Edema
01/2023 - 01/2017
5Infections
06/2021 - 12/2007
5Hereditary Corneal Dystrophies
06/2018 - 12/2007
4Blindness (Hysterical Blindness)
03/2024 - 10/2005
4Limbal Stem Cell Deficiency
01/2024 - 02/2008
4Diabetic Retinopathy (Retinopathy, Diabetic)
01/2022 - 04/2014
4Hypersensitivity (Allergy)
05/2017 - 08/2004
3Corneal Opacity
01/2024 - 01/2015
3Pain (Aches)
01/2023 - 10/2019
3COVID-19
01/2022 - 07/2020
3Eye Diseases (Eye Disease)
01/2022 - 05/2015
2Cicatrix (Scar)
06/2023 - 01/2018
2Proliferative Vitreoretinopathy
05/2023 - 09/2017
2Pterygium
02/2023 - 01/2021
2Postoperative Pain
01/2023 - 10/2019
2Astigmatism
09/2022 - 01/2014
2Blister (Bulla)
12/2020 - 01/2019
2Ocular Hypertension (Glaucoma, Suspect)
02/2019 - 12/2016
2Chemical Burns (Chemical Burn)
01/2019 - 02/2008
2Retinal Diseases
05/2018 - 04/2014
2Atopic Dermatitis (Atopic Eczema)
05/2017 - 04/2009
2Disease Progression
01/2017 - 12/2014
2Nevus (Nevi)
04/2014 - 05/2002
1Myofibromatosis
05/2024

Drug/Important Bio-Agent (IBA)

15Ophthalmic Solutions (Eye Drops)IBA
06/2023 - 12/2007
9Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 05/2009
9Bevacizumab (Avastin)FDA Link
01/2022 - 06/2007
7Retinaldehyde (Retinal)IBA
04/2024 - 04/2014
7Proteins (Proteins, Gene)FDA Link
12/2023 - 10/2005
5SteroidsIBA
06/2023 - 03/2016
5CollagenIBA
01/2022 - 01/2011
5GS 101IBA
09/2014 - 09/2009
4AntigensIBA
01/2023 - 08/2004
4Biomarkers (Surrogate Marker)IBA
03/2021 - 05/2014
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2017 - 10/2005
4CytokinesIBA
09/2017 - 01/2014
3Hyaluronan ReceptorsIBA
12/2020 - 07/2002
32,4- diamino- 5- cyclohexyl- 6- methylpyrimidineIBA
05/2018 - 12/2016
3Vascular Endothelial Growth Factor CIBA
01/2016 - 04/2004
3Thrombospondin 1IBA
09/2015 - 04/2004
3Antisense OligonucleotidesIBA
09/2014 - 09/2009
2Mitomycin (Mitomycin-C)FDA LinkGeneric
03/2024 - 10/2022
2Sulfur HexafluorideIBA
01/2022 - 01/2019
2Complement System Proteins (Complement)IBA
05/2021 - 03/2021
2Dexamethasone (Maxidex)FDA LinkGeneric
05/2019 - 04/2014
2Clostridium sordellii lethal toxin LTIBA
02/2019 - 12/2016
2Monophenol Monooxygenase (Tyrosinase)IBA
01/2019 - 09/2015
2Riboflavin (Vitamin B2)FDA LinkGeneric
12/2018 - 03/2009
2Transforming Growth Factor beta (TGF-beta)IBA
09/2017 - 02/2016
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2017 - 08/2002
2Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA
01/2017 - 08/2004
2N-formyl-13-dihydrocarminomycin (NFD)IBA
09/2015 - 12/2014
2Insulin Receptor Substrate ProteinsIBA
09/2014 - 09/2009
2Cyclosporine (Ciclosporin)FDA LinkGeneric
09/2014 - 03/2012
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2014 - 07/2006
2Ranibizumab (Lucentis)FDA Link
03/2014 - 03/2012
2OptisolIBA
09/2013 - 07/2012
2Melanins (Melanin)IBA
05/2009 - 05/2002
1Imatinib Mesylate (Gleevec)FDA Link
05/2024
1Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
05/2024
1Trypan BlueFDA Link
01/2024

Therapy/Procedure

68Corneal Transplantation (Keratoplasty)
04/2024 - 10/2002
23Sutures (Suture)
06/2023 - 04/2004
21Therapeutics
12/2023 - 08/2002
9Trabeculectomy (Trabeculoplasty)
03/2024 - 09/2013
9Penetrating Keratoplasty
09/2022 - 02/2006
7Lasers (Laser)
05/2023 - 04/2007
5Phacoemulsification
04/2024 - 07/2012
5Transplantation
01/2024 - 09/2009
5Slit Lamp
02/2021 - 04/2014
3Excimer Lasers
01/2024 - 10/2002
3Diathermy
01/2022 - 08/2012
2Keratectomy
01/2024 - 03/2018
2Conservative Treatment
06/2023 - 06/2008
2Contact Lenses
06/2023 - 12/2022
2Refractive Surgical Procedures
12/2022 - 01/2019
2Ambulatory Surgical Procedures (Outpatient Surgery)
10/2019 - 02/2011
2Trephining
06/2012 - 10/2002
2Organ Transplantation
01/2011 - 07/2010
2Off-Label Use
10/2009 - 01/2008
2Drug Therapy (Chemotherapy)
06/2008 - 01/2003